Description

C-(5-Trifluoromethyl-Pyridin-3-Yl)-Methylamine CAS NO 766513-53-5 is a high-value trifluoromethylated pyridine derivative, a versatile and critical building block in modern synthetic chemistry. Its unique structure, featuring a reactive methylamine group adjacent to an electron-deficient pyridine ring substituted with a trifluoromethyl group, makes it indispensable for creating novel compounds with enhanced properties. This intermediate is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, oncology, and anti-inflammatory applications.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve metabolic stability and bioavailability.
• Ligand & Catalyst Development: Serves as a valuable scaffold for constructing complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and electronic materials that require specific fluorine-containing motifs.
• Chemical Biology & Proteomics: Utilized as a tagging or linking agent in the development of biochemical probes and affinity purification reagents.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Item	Detail
Product Name	C-(5-Trifluoromethyl-Pyridin-3-Yl)-Methylamine
CAS No.	766513-53-5
Molecular Formula	C8H7F3N2
Molecular Weight	188.15 g/mol
Synonyms	(5-(Trifluoromethyl)pyridin-3-yl)methanamine; 3-(Aminomethyl)-5-(trifluoromethyl)pyridine; 5-(Trifluoromethyl)-3-pyridinemethanamine; 3-Pyridinemethanamine, 5-(trifluoromethyl)-; (5-Trifluoromethyl-3-pyridyl)methylamine; 3-Aminomethyl-5-trifluoromethylpyridine; 5-Trifluoromethylnicotinylamine
EINECS	Contact for details

Quality Control

Our C-(5-Trifluoromethyl-Pyridin-3-Yl)-Methylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP guidelines where applicable, ensuring suitability for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.