Description

Cyclobutanecarboxylic Acid, 3-Amino-, Methyl Ester, trans- (9Ci) is a high-purity, stereochemically defined building block of significant interest in advanced organic synthesis. Its value lies in the unique, strained cyclobutane ring system and the presence of both amino and ester functional groups, which enable its use in constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and anti-infectives.
• Agrochemical Research: Used in the development of new herbicides and insecticides, leveraging the bioactive potential of the cyclobutane scaffold.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics: Incorporated into peptide backbones to induce specific conformational constraints and enhance metabolic stability.
• Material Science: Potential monomer or building block for specialty polymers with unique thermal and mechanical properties.
• Academic & Industrial R&D: Fundamental research tool for studying cyclobutane chemistry and ring-strain reactivity.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 3-Amino-, Methyl Ester, trans- (9Ci)
CAS No.	766458-70-2
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	trans-3-Aminocyclobutanecarboxylic Acid Methyl Ester; Methyl trans-3-Aminocyclobutanecarboxylate; (1r,3r)-3-Aminocyclobutanecarboxylic Acid Methyl Ester; (1s,3s)-3-Aminocyclobutanecarboxylic Acid Methyl Ester; 3-Amino-1-methyl cyclobutanecarboxylate; trans-3-ACBC Methyl Ester; 766458-70-2; Methyl 3-aminocyclobutanecarboxylate (trans)
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 3-Amino-, Methyl Ester, trans- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are provided to guarantee traceability and consistency for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (trans isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.