Description

Glycine, n-(2,2-Dimethylpropyl)-, Methyl Ester (9Ci) is a specialized amino acid derivative characterized by its neopentyl (2,2-dimethylpropyl) side chain and methyl ester functional group. This structural motif makes it a valuable non-natural, sterically hindered building block for advanced organic synthesis and pharmaceutical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical and life sciences sectors. The compound, with CAS number 765957-58-2, is engineered for applications requiring high-purity, customized molecular scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring bulky, lipophilic side chains to modulate bioavailability and receptor binding.
• Peptidomimetics & Bio-Conjugation: Used in the design and synthesis of peptidomimetic compounds, where its structure can mimic natural amino acids while conferring metabolic stability and altered physicochemical properties.
• Agrochemical Research: Acts as a building block for developing new crop protection agents and herbicides, where the neopentyl group can influence the compound's environmental fate and biological activity.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs), leveraging its defined stereochemistry and functional handles.
• Material Science: Incorporated into polymers and specialty coatings to impart specific characteristics like rigidity, hydrophobicity, or compatibility.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds and molecular probes for studying biological pathways and enzyme mechanisms.

Basic Information

Product Name	Glycine, n-(2,2-Dimethylpropyl)-, Methyl Ester (9Ci)
CAS No.	765957-58-2
Molecular Formula	C8H17NO2
Molecular Weight	159.23 g/mol
Synonyms	N-Neopentylglycine methyl ester; Methyl 2-[(2,2-dimethylpropyl)amino]acetate; 2-[(2,2-Dimethylpropyl)amino]acetic acid methyl ester; Glycine, N-(2,2-dimethylpropyl)-, methyl ester; Methyl N-neopentylglycinate; (2,2-Dimethylpropylamino)-acetic acid methyl ester; N-(2,2-Dimethylpropyl)glycine methyl ester
EINECS	Contact for details

Quality Control

Our Glycine, n-(2,2-Dimethylpropyl)-, Methyl Ester (9Ci) is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. We provide full traceability and Certificates of Analysis (COA) are available for every shipment upon request, detailing all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.