Description

Cyclopropanecarboxylic Acid, 1-[(Trimethylsilyl)Amino]-, Ethyl Ester (9Ci) is a specialized organosilicon building block featuring a cyclopropane ring and a protected amino group. This compound is valued for its unique steric and electronic properties, which are leveraged in advanced synthetic chemistry to construct complex molecular architectures. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and catalyst design.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those containing strained ring systems.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that require cyclopropane motifs for biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research of advanced polymers and silicon-based hybrid materials with tailored properties.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis, including cycloaddition and cross-coupling reactions.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 1-[(Trimethylsilyl)Amino]-, Ethyl Ester (9Ci)
CAS No.	765242-60-2
Molecular Formula	C9H19NO2Si
Molecular Weight	201.34 g/mol
Synonyms	Ethyl 1-[(Trimethylsilyl)amino]cyclopropanecarboxylate; 1-(Trimethylsilylamino)cyclopropanecarboxylic Acid Ethyl Ester; 1-Amino-1-(trimethylsilyl)cyclopropanecarboxylic Acid Ethyl Ester; 1-(TMS-amino)cyclopropanecarboxylic Acid Ethyl Ester; Cyclopropanecarboxylic acid, 1-[(trimethylsilyl)amino]-, ethyl ester; Ethyl 1-(trimethylsilylamino)cyclopropanecarboxylate; 1-(Trimethylsilylamino)cyclopropanecarboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our production of Cyclopropanecarboxylic Acid, 1-[(Trimethylsilyl)Amino]-, Ethyl Ester (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for critical R&D and scale-up processes. Each lot is characterized by advanced analytical techniques including NMR, HPLC, and GC-MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.