Description

2-(2-Methoxypyridin-4-Yl)Acetonitrile is a high-purity pyridine derivative building block essential for advanced organic synthesis. This compound serves as a critical intermediate in the development of complex molecules, particularly within the pharmaceutical and agrochemical sectors. It is primarily sought after by R&D chemists and process development scientists for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents. Its specific structure offers a versatile handle for further functionalization, enabling the creation of targeted libraries for drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyridine moiety for bioactivity.
• Material Science: Serves as a precursor for functionalized ligands and monomers used in advanced polymers and coordination chemistry.
• Chemical Synthesis: A versatile nitrile-containing synthon for heterocyclic chemistry, enabling reactions like cycloadditions and nucleophilic additions.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and exploratory research projects.

Basic Information

Product Name	2-(2-Methoxypyridin-4-Yl)Acetonitrile
CAS No.	764708-18-1
Molecular Formula	C8H8N2O
Molecular Weight	148.16 g/mol
Synonyms	4-(Cyanomethyl)-2-methoxypyridine; 2-Methoxy-4-pyridineacetonitrile; (2-Methoxypyridin-4-yl)acetonitrile; 4-Pyridineacetonitrile, 2-methoxy-; 2-Methoxy-4-pyridylacetonitrile; 2-Methoxypyridine-4-acetonitrile; 764708-18-1
EINECS	Contact for details

Quality Control

Our 2-(2-Methoxypyridin-4-Yl)Acetonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis by GC. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your internal specifications and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.