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3-Pyrrolylboronic Acid CAS NO 763120-55-4
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CAS No.:763120-55-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3-Pyrrolylboronic Acid is a versatile and valuable organoboron building block, essential for modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecular architectures through cross-coupling reactions, a cornerstone of pharmaceutical and agrochemical research. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional molecules.
Application
- Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel pyrrole-containing drug candidates and active pharmaceutical ingredients (APIs).
- Agrochemical Synthesis: Used to construct complex heterocyclic scaffolds found in advanced herbicides, fungicides, and insecticides.
- Material Science Research: Serves as a building block for creating organic electronic materials, conductive polymers, and advanced organic frameworks (MOFs/COFs).
- Chemical Biology & Probe Development: Employed in the synthesis of molecular probes and bioconjugates for studying biological processes and target engagement.
- Catalyst Ligand Synthesis: Used to prepare specialized N-heterocyclic ligands for transition metal catalysis.
- Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
Basic Information
| Product Name | 3-Pyrrolylboronic Acid |
| CAS No. | 763120-55-4 |
| Molecular Formula | C4H6BNO2 |
| Molecular Weight | 110.91 g/mol |
| Synonyms | 1H-Pyrrol-3-ylboronic Acid; 3-Boronopyrrole; 3-Pyrroleboronic Acid; (1H-Pyrrol-3-yl)boronic Acid; 3-Pyrrolyl-B(OH)2; Boronic acid, B-(1H-pyrrol-3-yl)-; 3-Pyrrolylboronic acid pinacol ester (precursor); 3-Pyrrolyl-BA |
| EINECS | Contact for details |
Quality Control
Our 3-Pyrrolylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder or crystalline solid |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥95% (Typical 97-99%) |
| Assay (NMR) | ≥95% |
| Water Content (KF) | ≤1.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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