Description

Spiro[2.2]Pentanecarboxylic Acid, 1-Amino-, Methyl Ester (9Ci) is a specialized spirocyclic organic compound featuring a unique bridged bicyclic structure combined with both amino and ester functional groups. This molecular architecture makes it a valuable and versatile building block in advanced organic synthesis, particularly for constructing complex, three-dimensional frameworks. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially those requiring rigid, spirocyclic cores to modulate biological activity and pharmacokinetic properties.
• Agrochemical Research: Used in the synthesis of new-generation herbicides, fungicides, and insecticides, where its unique structure can contribute to enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized chelating ligands and organocatalysts used in asymmetric synthesis.
• Material Science: Employed in the research and development of advanced polymers and functional materials with specific thermal or mechanical properties derived from its rigid backbone.
• Chemical Biology Probe Synthesis: Utilized to build molecular probes for studying enzyme function and biological pathways due to its potential for selective functionalization.

Basic Information

Product Name	Spiro[2.2]Pentanecarboxylic Acid, 1-Amino-, Methyl Ester (9Ci)
CAS No.	763077-20-9
Molecular Formula	C8H13NO2
Molecular Weight	155.19 g/mol
Synonyms	1-Aminospiro[2.2]pentane-1-carboxylic acid methyl ester; Methyl 1-aminospiro[2.2]pentane-1-carboxylate; 1-Amino-1-(methoxycarbonyl)spiro[2.2]pentane; Spiro[2.2]pentane-1-carboxylic acid, 1-amino-, methyl ester; Amino-spiro[2.2]pentane methyl ester carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of Spiro[2.2]Pentanecarboxylic Acid, 1-Amino-, Methyl Ester is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.