Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methylpropyl Ester, (1R,2R,4R)-Rel- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its rigid bicyclic framework and specific stereochemistry make it a valuable precursor for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical development teams for applications in medicinal chemistry, asymmetric catalysis, and the synthesis of novel materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of active pharmaceutical ingredients (APIs), particularly those requiring a rigid, functionalized norbornene core.
• Asymmetric Synthesis: Serves as a precursor or ligand component in catalytic systems for creating enantiomerically pure compounds.
• Advanced Material Research: Used in the development of specialty polymers, resins, and functional materials where the norbornene structure imparts specific thermal or mechanical properties.
• Agrochemical Synthesis: Employed in the design and synthesis of novel, stereospecific crop protection agents and herbicides.
• Flavor & Fragrance Chemistry: Acts as a building block for synthesizing complex, naturally-derived odorants and flavor compounds.
• Academic & Industrial R&D: A versatile tool for methodological studies in organic chemistry and the exploration of new chemical spaces.

Basic Information

Item	Details
Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-Methylpropyl Ester, (1R,2R,4R)-Rel- (9Ci)
CAS No.	762261-06-3
Molecular Formula	C12H18O2
Molecular Weight	194.27 g/mol
Synonyms	(1R,2R,4R)-rel-2-Methylpropyl bicyclo[2.2.1]hept-5-ene-2-carboxylate; Isobutyl endo-Norborne-5-ene-2-carboxylate; (1R,2R,4R)-rel-Isobutyl 5-norbornene-2-carboxylate; endo-Isobutyl 5-norbornene-2-carboxylate; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, isobutyl ester, (1R,2R,4R)-rel-; 5-Norbornene-2-carboxylic acid, isobutyl ester, endo-; Chiral Isobutyl Norbornene Carboxylate; Norbornene Isobutyl Ester Derivative
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Quality is verified through advanced analytical techniques including chiral HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with each shipment to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% e.e.
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.