Description

1-Benzyl-1H-Pyrazole-4-Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and this boronic ester, crucial for synthesizing biphenyl and heterobiaryl scaffolds.
• Pharmaceutical Intermediate: Used in the research and development of active pharmaceutical ingredients (APIs), particularly those containing pyrazole and benzyl-protected heterocyclic motifs.
• Agrochemical Synthesis: Employed in creating novel herbicides, fungicides, and insecticides that require specific pyrazole-based structures.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing specialized ligands used in catalysis and material science.
• Chemical Biology Probes: Useful in the synthesis of molecular probes for studying biological systems and target engagement.
• Polymer and Material Science: Incorporated into monomers for creating functional polymers with tailored electronic or photophysical properties.

Basic Information

Item	Detail
Product Name	1-Benzyl-1H-Pyrazole-4-Boronic Acid Pinacol Ester
CAS No.	761446-45-1
Molecular Formula	C16H21BN2O2
Molecular Weight	284.16 g/mol
Synonyms	1-Benzyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Benzyl-1H-pyrazol-4-ylboronic acid pinacol ester; 1-Benzyl-4-(pinacolboranyl)-1H-pyrazole; 1-Benzylpyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-benzyl-1H-pyrazole; 1-Benzyl-1H-4-pyrazoleboronic acid pinacol ester; (1-Benzyl-1H-pyrazol-4-yl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Benzyl-1H-Pyrazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available for every lot upon request, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.