Description

1-Methyl-4-Pyrazole Boronic Acid Pinacol Ester is a high-purity, protected boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the efficient construction of complex molecular architectures. It is primarily utilized by research scientists and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for drug discovery and development programs.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: A key reagent for forming carbon-carbon bonds between aryl/heteroaryl halides and the pyrazole moiety, crucial for creating novel active pharmaceutical ingredients (APIs).
• Pharmaceutical Intermediate Synthesis: Used in the research and development of drug candidates, particularly those containing functionalized pyrazole heterocycles for various therapeutic targets.
• Agrochemical Active Ingredient Development: Employed in the synthesis of novel herbicides, fungicides, and insecticides that require specific heterocyclic frameworks.
• Ligand and Catalyst Preparation: Acts as a precursor for synthesizing specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Utilized in the development of organic electronic materials, such as OLEDs and semiconductors, where precise molecular structure is paramount.
• Chemical Biology and Probe Development: Serves as a versatile handle for bioconjugation and the creation of molecular probes for studying biological systems.

Basic Information

Product Name	1-Methyl-4-Pyrazole Boronic Acid Pinacol Ester
CAS No.	761446-44-0
Molecular Formula	C₁₀H₁₇BN₂O₂
Molecular Weight	208.07 g/mol
Synonyms	1-Methyl-1H-pyrazole-4-boronic acid pinacol ester; 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-methyl-1H-pyrazole; 1-Methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-Methyl-1H-pyrazol-4-ylboronic acid pinacol ester; 1-Methylpyrazole-4-boronic acid pinacol ester; Pinacol 1-Methyl-1H-pyrazole-4-boronate; 1-Methyl-4-pyrazoleboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 1-Methyl-4-Pyrazole Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for prolonged storage or after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.