Description

4-(4-Chlorophenyl)Piperidine-4-Carboxylic Acid is a high-purity, synthetically versatile piperidine derivative that serves as a critical building block in modern organic synthesis. Its unique structure, featuring both a carboxylic acid and a chlorophenyl group on the piperidine scaffold, makes it an indispensable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and metabolic disorder research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting neurological receptors and enzymes.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its halogenated aromatic system.
• Ligand & Catalyst Development: Serves as a sophisticated ligand or a core structure for creating chiral catalysts in asymmetric synthesis.
• Chemical Biology Probes: Utilized to create molecular probes for studying protein function and biological pathways.
• Material Science Research: Investigated as a monomer or additive for creating specialized polymers with unique thermal or mechanical properties.

Basic Information

Item	Details
Product Name	4-(4-Chlorophenyl)Piperidine-4-Carboxylic Acid
CAS No.	760943-97-3
Molecular Formula	C12H14ClNO2
Molecular Weight	239.70 g/mol
Synonyms	4-(4-Chlorophenyl)-4-piperidinecarboxylic acid; 4-(p-Chlorophenyl)isonipecotic acid; 4-Carboxy-4-(4-chlorophenyl)piperidine; 4-(4-Chlorophenyl)piperidine-4-carboxylic acid; 1-(4-Chlorophenyl)-4-piperidinecarboxylic acid; 4-(4-Chlorophenyl)-4-piperidinecarboxylic acid; 4-Piperidinecarboxylic acid, 4-(4-chlorophenyl)-
EINECS	Contact for details

Quality Control

Every batch of 4-(4-Chlorophenyl)Piperidine-4-Carboxylic Acid is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent in-house specifications, which are aligned with the standards expected for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is compatible with strong acids and organic solvents but should be handled with appropriate precautions to avoid contamination and moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.