Description

Methyl (2S)-2-Amino-3-(2-Chlorophenyl)Propanoate CAS NO 760939-41-1 is a high-purity chiral amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a stereochemically defined scaffold for constructing complex molecules with precise biological activity. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel therapeutic agents, including protease inhibitors and CNS-active compounds.
• Peptidomimetics Research: Used in the design and synthesis of peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Building block for creating chiral herbicides, fungicides, and plant growth regulators with improved efficacy.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in stereoselective chemical transformations.
• Chemical Biology Probes: Utilized to create labeled or modified amino acid derivatives for studying biological pathways and enzyme mechanisms.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific target molecules under cGMP conditions where applicable.

Basic Information

Product Name	Methyl (2S)-2-Amino-3-(2-Chlorophenyl)Propanoate
CAS No.	760939-41-1
Molecular Formula	C10H12ClNO2
Molecular Weight	213.66 g/mol
Synonyms	(S)-Methyl 2-amino-3-(2-chlorophenyl)propanoate; L-2-Chlorophenylalanine methyl ester; Methyl (S)-2-amino-3-(2-chlorophenyl)propionate; (2S)-2-Amino-3-(2-chlorophenyl)propanoic acid methyl ester; 2-Chloro-DL-phenylalanine methyl ester (stereoisomer); 760939-41-1; Methyl L-α-amino-2-chlorohydrocinnamate
EINECS	Contact for details

Quality Control

Our Methyl (2S)-2-Amino-3-(2-Chlorophenyl)Propanoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided and can be tailored to meet specific client or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (HPLC)	≥99.0% ee
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤10 ppm
Single Unknown Impurity (HPLC)	≤0.5%
Total Impurities (HPLC)	≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.