Description

2-Chloro-5-(2-thiazolyl)pyridine is a high-value heterocyclic building block featuring a pyridine core substituted with both a chloro group and a thiazole moiety. This compound matters as a critical intermediate in the synthesis of advanced pharmaceutical compounds, particularly in the development of kinase inhibitors and other biologically active molecules. It is primarily needed by research institutions, pharmaceutical development companies, and fine chemical manufacturers engaged in the creation of novel therapeutic agents and agrochemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a ligand precursor or a functional unit in the design of metal-organic frameworks (MOFs) and coordination polymers.
• Organic Electronics: Investigated as a building block for electron-transport materials in OLEDs and other electronic devices due to its conjugated system.
• Chemical Biology: Employed in the synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scale-up and production of client-specific target molecules.

Basic Information

Product Name	2-Chloro-5-(2-thiazolyl)pyridine
CAS No.	760193-03-1
Molecular Formula	C8H5ClN2S
Molecular Weight	196.66 g/mol
Synonyms	2-Chloro-5-(thiazol-2-yl)pyridine; 5-(2-Thiazolyl)-2-chloropyridine; 2-(5-Chloropyridin-2-yl)thiazole; 2-Chloro-5-(1,3-thiazol-2-yl)pyridine; Pyridine, 2-chloro-5-(2-thiazolyl)-; 2-Chloro-5-(thiazol-2-yl)pyridine; 2-(2-Chloropyridin-5-yl)thiazole
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(2-thiazolyl)pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.