Description

Cyclopropanecarboxylic Acid, 2-(1-Fluoroethenyl)-2-Methyl-, Methyl Ester is a high-value, fluorinated cyclopropane derivative, a key structural motif prized in modern synthetic chemistry for its unique three-membered ring strain and fluorine atom incorporation. This compound serves as a sophisticated advanced pharmaceutical intermediate (API) and a versatile building block for constructing complex molecules with tailored biological and physical properties. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors to introduce the cyclopropyl and fluoroalkene functionalities into target molecules.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, where the cyclopropane ring can enhance metabolic stability and biological activity.
• Fluorinated Material Precursor: Serves as a monomer or precursor for specialty polymers and advanced materials that require fluorinated segments to impart chemical resistance, low surface energy, or specific optical properties.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization to explore the effects of the strained cyclopropane and fluoroethenyl groups on potency and pharmacokinetics.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Ligand and Catalyst Development: Can be utilized in the preparation of novel chiral ligands or organocatalysts for asymmetric synthesis applications.

Basic Information

Product Name	Cyclopropanecarboxylic Acid, 2-(1-Fluoroethenyl)-2-Methyl-, Methyl Ester
CAS No.	760179-41-7
Molecular Formula	C8H11FO2
Molecular Weight	158.17 g/mol
Synonyms	2-(1-Fluoroethenyl)-2-methylcyclopropanecarboxylic acid methyl ester; Methyl 2-(1-fluoroethenyl)-2-methylcyclopropanecarboxylate; 2-Methyl-2-(1-fluorovinyl)cyclopropanecarboxylic Acid Methyl Ester; 760179-41-7; Fluorinated cyclopropane ester; Cyclopropane carboxylic acid methyl ester derivative
EINECS	Contact for details

Quality Control

We maintain a strict quality management system to ensure batch-to-batch consistency and high purity for research and development applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with exacting customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.