Description

3-Chloro-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its unique combination of a carboxylic acid group and halogenated substituents. This compound matters as a critical intermediate in modern synthetic chemistry, enabling the construction of complex molecules with tailored properties for advanced applications. It is primarily needed by R&D and production teams in the pharmaceutical and agrochemical industries for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl and chloro groups enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or organic light-emitting diodes (OLEDs).
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	3-Chloro-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid
CAS No.	760147-01-1
Molecular Formula	C7H3ClF3NO2
Molecular Weight	225.55 g/mol
Synonyms	2-Pyridinecarboxylic acid, 3-chloro-6-(trifluoromethyl)-; 3-Chloro-6-(trifluoromethyl)picolinic acid; 3-Chloro-6-(trifluoromethyl)pyridine-2-carboxylic acid; 3-Chloro-6-trifluoromethyl-2-pyridinecarboxylic acid; 3-Chloro-6-trifluoromethylpicolinic acid; 760147-01-1; 3-Chloro-6-trifluoromethylpyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Chloro-6-Trifluoromethyl-Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.