Description

2-Azaspiro[3.5]Nonane-1-Carboxylicacid(9Ci) is a high-value, nitrogen-containing spirocyclic building block of significant interest in advanced organic synthesis. Its unique constrained spirocyclic scaffold is crucial for modulating the physicochemical properties and biological activity of target molecules. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for constructing complex, three-dimensional molecular architectures in drug discovery programs, particularly for central nervous system (CNS) and metabolic disease targets.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the spirocyclic structure can confer improved stability and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis.
• Material Science: Potential building block for specialty polymers and advanced organic materials requiring rigid, functionalized components.
• Chemical Biology: Employed as a molecular probe or a core structure in fragment-based drug discovery (FBDD) due to its high sp3 character.

Basic Information

Product Name	2-Azaspiro[3.5]Nonane-1-Carboxylicacid(9Ci)
CAS No.	759444-46-7
Molecular Formula	C9H15NO2
Molecular Weight	169.22 g/mol
Synonyms	1-Carboxy-2-azaspiro[3.5]nonane; 2-Azaspiro[3.5]nonane-1-carboxylic acid; 2-Azaspiro[3.5]nonane-1-carboxylicacid(9CI); Azaspiro[3.5]nonane-1-carboxylic acid; 1-Azaspiro[3.5]nonane-2-carboxylic acid (tautomer); Spirocyclic proline derivative
EINECS	Contact for details

Quality Control

We supply 2-Azaspiro[3.5]Nonane-1-Carboxylicacid(9Ci) in high-purity grades suitable for research and development. Our products undergo rigorous quality testing to ensure batch-to-batch consistency and compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.