Description

1-Oxaspiro[2.2]Pentane, 2-(Difluoromethyl)-2-Methyl- is a specialized spirocyclic ether building block featuring a difluoromethyl group. This compound is valued for its unique three-dimensional structure and the introduction of fluorine atoms, which are critical for modulating the physicochemical and biological properties of advanced materials and pharmaceuticals. It is primarily sought by research chemists and process development scientists in the agrochemical and pharmaceutical industries for use in medicinal chemistry, pesticide development, and the synthesis of novel fluorinated materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for introducing fluorinated spirocyclic motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides where the difluoromethyl-spirocyclic structure can enhance activity and environmental stability.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, or other advanced materials with tailored properties.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and lead optimization to improve metabolic stability, bioavailability, and binding affinity.
• Fluorine Chemistry: A valuable substrate for exploring new fluorination reactions and synthesizing complex fluoroorganic molecules.

Basic Information

Product Name	1-Oxaspiro[2.2]Pentane, 2-(Difluoromethyl)-2-Methyl-
CAS No.	758709-86-3
Molecular Formula	C6H8F2O
Molecular Weight	134.12 g/mol
Synonyms	2-(Difluoromethyl)-2-methyl-1-oxaspiro[2.2]pentane; 2-Methyl-2-(difluoromethyl)oxirane?; Spiro[cyclopropane-1,2'-oxirane], 2'-(difluoromethyl)-2'-methyl-; Difluoromethyl-methyl-oxaspiropentane; Oxaspiropentane, difluoromethyl methyl derivative
EINECS	Contact for details

Quality Control

Our 1-Oxaspiro[2.2]Pentane, 2-(Difluoromethyl)-2-Methyl- is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatography (GC/HPLC) and spectroscopy (NMR, IR), to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.