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5-Bromo-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine CAS NO 757978-18-0


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CAS No.:757978-18-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-Bromo-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a high-value halogenated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceutical agents and functional materials, enabling precise molecular modifications. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

  • Pharmaceutical Intermediate: A crucial precursor in the synthesis of kinase inhibitors and other targeted therapeutic small molecules.
  • Agrochemical Research: Used in the development of new active ingredients for crop protection products.
  • Material Science: Serves as a building block for organic electronic materials, such as those used in OLEDs and semiconductors.
  • Chemical Biology: Employed in the design and synthesis of molecular probes and labeled compounds for biological studies.
  • Cross-Coupling Reactions: Utilized in palladium-catalyzed reactions (e.g., Suzuki, Sonogashira) due to its reactive bromo and iodo substituents.
  • Library Synthesis: A valuable scaffold for generating diverse compound libraries in drug discovery programs.

Basic Information

Product Name 5-Bromo-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No. 757978-18-0
Molecular Formula C7H4BrIN2
Molecular Weight 322.93 g/mol
Synonyms 5-Bromo-3-iodo-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-bromo-3-iodo-; 5-Bromo-3-iodo-7-azaindole; 3-Iodo-5-bromo-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-3-iodo-1H-7-azaindole; 757978-18-0; 5-Br-3-I-7-azaindole
EINECS Contact for details

Quality Control

Our 5-Bromo-3-Iodo-1H-Pyrrolo[2,3-B]Pyridine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item Specification
Appearance Off-white to light yellow crystalline powder
Identification (IR) Conforms to structure
Identification (NMR) Conforms to structure
Purity (HPLC) ≥ 97.0%
Melting Point Contact for details
Heavy Metals < 20 ppm
Residual Solvents Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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