Description

Methyl 3-Amino-3-(5-Bromopyridin-3-Yl)Propanoate (Wx191893) is a high-purity, advanced pharmaceutical intermediate featuring a brominated pyridine core and an amino ester functional group. This compound is of critical importance for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of targeted small molecule drugs, especially kinase inhibitors and other enzyme modulators.
• Medicinal Chemistry Research: Used in hit-to-lead optimization and structure-activity relationship (SAR) studies to explore new therapeutic candidates.
• Agrochemical Synthesis: Serves as a precursor for developing novel crop protection agents and pesticides with specific biological activity.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects.
• Academic Research: Employed in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Methyl 3-Amino-3-(5-Bromopyridin-3-Yl)Propanoate (Wx191893)
CAS No.	757174-43-9
Molecular Formula	C9H11BrN2O2
Molecular Weight	259.10 g/mol
Synonyms	Methyl 3-amino-3-(5-bromo-3-pyridinyl)propanoate; 3-(5-Bromopyridin-3-yl)-3-aminopropionic acid methyl ester; 5-Bromo-3-pyridinepropanoic acid, 3-amino-, methyl ester; Methyl β-amino-β-(5-bromo-3-pyridyl)propionate; WX-191893; Wx191893
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-3-(5-Bromopyridin-3-Yl)Propanoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.