Description

Carbamic Acid, [(2R,3R)-2-Hydroxy-3-Methyl-4-Pentenyl]-, 1,1-Dimethylethyl Ester is a specialized chiral building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the production of complex, biologically active molecules, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing stereochemically defined molecular architectures.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), especially in antiviral, anticancer, and anti-inflammatory drug discovery pipelines.
• Agrochemical Synthesis: Used in the research and development of advanced, stereoselective pesticides and herbicides where specific chirality impacts biological activity.
• Peptidomimetics & Prodrug Development: Serves as a protected amino acid derivative or a carbamate-based prodrug linker in medicinal chemistry.
• Asymmetric Catalysis Research: Employed as a substrate or ligand precursor in the development and testing of new chiral catalysts and synthetic methodologies.
• Fine Chemical Manufacturing: Utilized in the custom synthesis of high-value, complex organic molecules for various research and industrial applications.

Basic Information

Product Name	Carbamic Acid, [(2R,3R)-2-Hydroxy-3-Methyl-4-Pentenyl]-, 1,1-Dimethylethyl Ester
CAS No.	756834-76-1
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	tert-Butyl (2R,3R)-2-hydroxy-3-methylpent-4-en-1-ylcarbamate; (2R,3R)-N-Boc-2-Hydroxy-3-methyl-4-penten-1-amine; (2R,3R)-2-Hydroxy-3-methyl-4-pentenylcarbamic acid tert-butyl ester; Boc-DHMPA; (2R,3R)-1-((tert-Butoxycarbonyl)amino)-2-hydroxy-3-methylpent-4-ene; N-Boc-(2R,3R)-2-Hydroxy-3-methyl-4-pentenylamine; tert-Butyl ((2R,3R)-2-hydroxy-3-methylpent-4-en-1-yl)carbamate
EINECS	Contact for details

Quality Control

Our Carbamic Acid, [(2R,3R)-2-Hydroxy-3-Methyl-4-Pentenyl]-, 1,1-Dimethylethyl Ester is produced under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including chiral HPLC to confirm enantiomeric excess and identity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.