Description

1(2H)-Pyridinecarboxylic Acid, 3,6-Dihydro-4-Hydroxy-, Ethyl Ester is a specialized pyridine derivative ester, serving as a versatile and high-value synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and life science industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new-generation pesticides and herbicides, leveraging its heterocyclic core for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating complex ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, dyes, and functional polymers.
• Academic & Contract Research: A valuable reagent for methodological studies and discovery chemistry in university and CRO (Contract Research Organization) laboratories.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	1(2H)-Pyridinecarboxylic Acid, 3,6-Dihydro-4-Hydroxy-, Ethyl Ester
CAS No.	756774-28-4
Molecular Formula	C8H11NO3
Molecular Weight	169.18 g/mol
Synonyms	4-Hydroxy-3,6-dihydro-2H-pyridine-1-carboxylic acid ethyl ester; Ethyl 4-hydroxy-1,2,3,6-tetrahydropyridine-1-carboxylate; 4-Hydroxy-1,2,3,6-tetrahydropyridine-1-carboxylic acid ethyl ester; 1-Carbethoxy-4-hydroxy-1,2,3,6-tetrahydropyridine; 1-Ethoxycarbonyl-4-hydroxy-1,2,3,6-tetrahydropyridine; 4-Hydroxy-1-ethoxycarbonyl-1,2,3,6-tetrahydropyridine; 756774-28-4
EINECS	Contact for details

Quality Control

Our 1(2H)-Pyridinecarboxylic Acid, 3,6-Dihydro-4-Hydroxy-, Ethyl Ester is produced under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request. We support custom synthesis and can tailor purity grades to meet specific research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.