Description

5-Bromo-3-(1-(2,6-Dichloro-3-Fluorophenyl)Ethoxy)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its complex halogenated aromatic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of targeted small-molecule therapeutics. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in oncology and targeted therapy research.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its unique halogen-substituted scaffold.
• Kinase Inhibitor Development: Serves as a precursor in the synthesis of potential kinase inhibitors, leveraging the pyridine and fluorophenyl motifs.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific molecule assembly.
• Chemical Reference Standard: Used as an analytical standard for quality control and method development in API manufacturing.
• Bioconjugation & Probe Development: Potential use in creating chemical probes for biochemical and cellular assays.

Basic Information

Product Name	5-Bromo-3-(1-(2,6-Dichloro-3-Fluorophenyl)Ethoxy)Pyridin-2-Amine
CAS No.	756503-69-2
Molecular Formula	C13H10BrCl2FN2O
Molecular Weight	380.04 g/mol
Synonyms	5-Bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridin-2-amine; 2-Amino-5-bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]pyridine; 756503-69-2; 5-Bromo-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-2-pyridinamine; 2-Pyridinamine, 5-bromo-3-[1-(2,6-dichloro-3-fluorophenyl)ethoxy]-
EINECS	Contact for details

Quality Control

Our 5-Bromo-3-(1-(2,6-Dichloro-3-Fluorophenyl)Ethoxy)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.