Description

Piperidine, 4-(1H-1,2,3-Triazol-1-Yl)- (9Ci) is a specialized heterocyclic building block that combines a piperidine scaffold with a 1,2,3-triazole moiety. This unique molecular architecture makes it a valuable intermediate for the synthesis of novel compounds in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists working in medicinal chemistry and fine chemical synthesis. The compound's structure offers a versatile handle for further functionalization, enabling the exploration of new chemical space for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to introduce specific pharmacophores and modulate the physicochemical properties of drug candidates.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Ligand and Catalyst Development: Employed in the creation of novel ligands for transition metal catalysis and organocatalysts due to the coordinating potential of the triazole nitrogen atoms.
• Material Science: Can be incorporated into polymers or functional materials to impart specific chemical or electronic properties.
• Chemical Biology Probes: Used in the synthesis of molecular probes for studying biological pathways and target engagement, often via click chemistry conjugation.

Basic Information

Product Name	Piperidine, 4-(1H-1,2,3-Triazol-1-Yl)- (9Ci)
CAS No.	756476-21-8
Molecular Formula	C7H12N4
Molecular Weight	152.20 g/mol
Synonyms	4-(1H-1,2,3-Triazol-1-yl)piperidine; 1-(Piperidin-4-yl)-1H-1,2,3-triazole; 4-(1,2,3-Triazol-1-yl)piperidine; 1-(1,2,3-Triazol-1-yl)-4-piperidine; 1-Piperidin-4-yl-1H-[1,2,3]triazole; 4-(1H-1,2,3-Triazol-1-yl)piperidine; 4-(1,2,3-Triazolyl)piperidine
EINECS	Contact for details

Quality Control

Our Piperidine, 4-(1H-1,2,3-Triazol-1-Yl)- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We support cGMP (current Good Manufacturing Practice) standards for advanced applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which may affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.