Description

2-Piperidinecarboxylicacid,4-(1-Methylethyl)-,(2S,4S)-(9Ci) is a high-purity, stereochemically defined chiral piperidine derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in asymmetric synthesis. It is essential for research and development chemists and manufacturers in the pharmaceutical and fine chemical industries, particularly for the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Asymmetric Catalysis: Used as a precursor for chiral ligands and organocatalysts in stereoselective chemical transformations.
• Medicinal Chemistry Research: A valuable scaffold for drug discovery programs, enabling the exploration of structure-activity relationships (SAR).
• Peptidomimetics: Incorporation into peptide analogs to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Intermediate in the production of chiral pesticides and herbicides.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in regulatory submissions.

Basic Information

Item	Detail
Product Name	2-Piperidinecarboxylicacid,4-(1-Methylethyl)-,(2S,4S)-(9Ci)
CAS No.	756464-00-3
Molecular Formula	C9H17NO2
Molecular Weight	171.24 g/mol
Synonyms	(2S,4S)-4-Isopropylpipecolic Acid; (2S,4S)-4-Isopropyl-2-piperidinecarboxylic Acid; L-4-Isopropylpipecolic Acid; (2S,4S)-4-(1-Methylethyl)-2-piperidinecarboxylic Acid; 4-Isopropyl-DL-pipecolic Acid (related); 4-Isopropylpipecolic Acid; A chiral non-proteinogenic amino acid derivative.
EINECS	Contact for details

Quality Control

Our 2-Piperidinecarboxylicacid,4-(1-Methylethyl)-,(2S,4S)-(9Ci) is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the material should be handled under a dry inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent moisture uptake. Recommended storage temperature: 2-8°C for extended stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% de
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.