Description

4-Pyridinecarboxamide,n-[2-[(Hydroxyamino)Carbonyl]Phenyl]-(9Ci) is a specialized organic compound with a molecular structure that incorporates both pyridine and hydroxamic acid functional groups. This unique architecture makes it a valuable intermediate for the synthesis of more complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel therapeutic agents, especially those targeting metalloenzymes.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of potential drug candidates, particularly for enzyme inhibitors.
• HDAC Inhibitor Research: Serves as a precursor or core structure in the development of histone deacetylase (HDAC) inhibitors for oncology and neurology applications.
• Metalloenzyme Inhibitor Development: Used in creating compounds designed to selectively bind and inhibit metalloenzymes involved in various disease pathways.
• Chemical Biology Probes: Utilized in the design of molecular probes to study biological processes and protein functions.
• Agrochemical Research: Investigated as an intermediate for developing novel active ingredients with specific biological activity.
• Academic & Contract Research: Employed in university laboratories and CROs (Contract Research Organizations) for fundamental chemical and medicinal chemistry studies.

Basic Information

Product Name	4-Pyridinecarboxamide,n-[2-[(Hydroxyamino)Carbonyl]Phenyl]-(9Ci)
CAS No.	754972-10-6
Molecular Formula	C13H11N3O3
Molecular Weight	257.25 g/mol
Synonyms	N-Hydroxy-2-[(pyridine-4-carbonyl)amino]benzamide; 2-[(4-Pyridinylcarbonyl)amino]-N-hydroxybenzamide; N1-Hydroxy-N2-(pyridine-4-carbonyl)isophthalamic acid; 4-Pyridinecarboxamide, N-[2-[(hydroxyamino)carbonyl]phenyl]-; CAS 754972-10-6; Hydroxamic acid derivative (pyridine-based); HDAC inhibitor intermediate
EINECS	Contact for details

Quality Control

Our 4-Pyridinecarboxamide,n-[2-[(Hydroxyamino)Carbonyl]Phenyl]-(9Ci) is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, assay, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.