Description

Methyl (2R)-2-Amino-3-(2-Hydroxyphenyl)Propanoate CAS NO 754927-44-1 is a chiral, non-proteinogenic amino acid ester derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which enable the precise construction of complex molecules with targeted biological activity. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in neurological and metabolic disorder therapeutics.
• Peptidomimetics & Drug Discovery: Used to incorporate the 2-hydroxyphenyl moiety into peptide backbones, creating novel peptidomimetics for drug discovery programs.
• Agrochemical Synthesis: Serves as a precursor in the synthesis of advanced, chiral herbicides and plant growth regulators.
• Catalyst & Ligand Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Biochemical Research: Utilized as a substrate or inhibitor analog in enzymatic studies and biochemical pathway research.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high stereochemical purity and reliable supply.

Basic Information

Product Name	Methyl (2R)-2-Amino-3-(2-Hydroxyphenyl)Propanoate
CAS No.	754927-44-1
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	(R)-Methyl 2-Amino-3-(2-hydroxyphenyl)propanoate; D-2-Hydroxyphenylglycine Methyl Ester; Methyl (R)-2-Amino-3-(2-hydroxyphenyl)propionate; (2R)-2-Amino-3-(2-hydroxyphenyl)propanoic Acid Methyl Ester; Methyl L-Dopa Methyl Ester Analog; (R)-α-Amino-2-hydroxybenzenepropanoic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our production of Methyl (2R)-2-Amino-3-(2-Hydroxyphenyl)Propanoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques including HPLC, chiral chromatography, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.