Description

1,4-Cyclohexadiene-1-Aceticacid,α-Amino-,Methylester,(S)-(9Ci) is a chiral, non-proteinogenic amino acid derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as chiral ligand synthesis, peptide mimetics, and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological and metabolic disorders.
• Chiral Ligand & Catalyst Precursor: Serves as a foundational structure for synthesizing enantioselective catalysts and ligands used in asymmetric synthesis.
• Peptidomimetics & Conformationally Restricted Peptides: Used to introduce unique steric and electronic properties into peptide backbones for drug discovery and biochemical probing.
• Agrochemical Research: Employed in the synthesis of advanced, chiral active ingredients for crop protection with potential for improved selectivity and environmental profile.
• Academic & Institutional Research: A valuable tool for methodological development in organic chemistry and for studying structure-activity relationships (SAR).
• Specialty Polymer Modification: Can be incorporated as a functional monomer to impart specific chiral or reactive sites into advanced polymer systems.

Basic Information

Product Name	1,4-Cyclohexadiene-1-Aceticacid,α-Amino-,Methylester,(S)-(9Ci)
CAS No.	754920-13-3
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(S)-Methyl 2-amino-2-(1,4-cyclohexadien-1-yl)acetate; (S)-1,4-Cyclohexadiene-1-glycine methyl ester; L-1,4-Cyclohexadienylglycine methyl ester; Methyl (S)-amino(1,4-cyclohexadien-1-yl)acetate; (S)-α-Amino-1,4-cyclohexadiene-1-acetic acid methyl ester; (9CI) identifier for this specific stereoisomer.
EINECS	Contact for details

Quality Control

Our production of 1,4-Cyclohexadiene-1-Aceticacid,α-Amino-,Methylester,(S)-(9Ci) adheres to stringent quality protocols suitable for research and development applications. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure consistency and reliability. Certificates of Analysis (COA) detailing specific batch results for identity, purity, and enantiomeric excess are available upon request. We support compliance with relevant guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee (S-isomer)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.