Description

5-(Chloromethyl)Pyridine-2-Carbaldehyde is a versatile and highly functionalized pyridine derivative, serving as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive aldehyde and a chloromethyl group, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the pyridine core is a common bioactive motif.
• Ligand and Catalyst Development: Serves as a starting material for creating novel chelating ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials due to its reactive handles.
• Chemical Biology Probes: Utilized for the design and synthesis of molecular probes and bioconjugation reagents for studying biological processes.

Basic Information

Product Name	5-(Chloromethyl)Pyridine-2-Carbaldehyde
CAS No.	754920-10-0
Molecular Formula	C7H6ClNO
Molecular Weight	155.58 g/mol
Synonyms	2-Pyridinecarboxaldehyde, 5-(chloromethyl)-; 5-(Chloromethyl)-2-pyridinecarboxaldehyde; 5-(Chloromethyl)picolinaldehyde; 2-Formyl-5-(chloromethyl)pyridine; 5-(Chloromethyl)-2-formylpyridine; 5-Chloromethylpyridine-2-carboxaldehyde; Picolinaldehyde, 5-(chloromethyl)-
EINECS	Contact for details

Quality Control

Our production of 5-(Chloromethyl)Pyridine-2-Carbaldehyde adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical parameters. Our quality system is designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. Keep away from heat, sparks, and open flames. Due to its sensitivity, allow the container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.