Description

(5-Bromo-2,3-Dioxo-2,3-Dihydro-Indol-1-Yl)-Acetic Acid Ethyl Ester is a high-purity, functionalized isatin derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a versatile brominated scaffold for constructing complex heterocyclic systems and pharmaceutical candidates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require precise building blocks for drug discovery and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition or possessing anti-cancer activity.
• Agrochemical Research: Used in the development of new herbicides and pesticides, leveraging its reactive bromine and carbonyl functionalities.
• Organic Synthesis Building Block: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic substitution reactions to introduce complex indole-based motifs.
• Material Science Precursor: Serves as a starting material for creating functional dyes, pigments, or organic electronic materials due to its conjugated isatin core.
• Biochemical Probe Development: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.

Basic Information

Product Name	(5-Bromo-2,3-Dioxo-2,3-Dihydro-Indol-1-Yl)-Acetic Acid Ethyl Ester
CAS No.	754235-62-6
Molecular Formula	C12H10BrNO4
Molecular Weight	312.12 g/mol
Synonyms	1-(Ethoxycarbonylmethyl)-5-bromoisatin; 5-Bromo-1-(carboxymethyl)isatin ethyl ester; Ethyl (5-bromo-2,3-dioxoindolin-1-yl)acetate; 5-Bromoisatin-1-acetic acid ethyl ester; 5-Bromo-1-carboxymethylisatin ethyl ester; 754235-62-6; 5-Bromo-N-(ethoxycarbonylmethyl)isatin
EINECS	Contact for details

Quality Control

Our (5-Bromo-2,3-Dioxo-2,3-Dihydro-Indol-1-Yl)-Acetic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, guaranteeing it meets the stringent requirements for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.