Description

3-Iodo-2-Phenoxypyridine is a versatile halogenated pyridine derivative, serving as a crucial synthetic intermediate in advanced organic chemistry. Its value lies in the strategic positioning of the iodine and phenoxy groups, which enable efficient cross-coupling reactions and functional group transformations. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for constructing complex heterocyclic scaffolds and developing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in developing novel pesticides and herbicides by acting as a precursor for functionalized pyridine cores.
• Material Science: Serves as a monomer or functionalizing agent in the creation of specialized polymers and organic electronic materials.
• Cross-Coupling Reactions: The iodine atom makes it an excellent substrate for Suzuki, Stille, and Sonogashira couplings to form new carbon-carbon bonds.
• Ligand Synthesis: Precursor for creating nitrogen- and oxygen-containing ligands used in catalysis and coordination chemistry.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes.

Basic Information

Product Name	3-Iodo-2-Phenoxypyridine
CAS No.	754214-57-8
Molecular Formula	C11H8INO
Molecular Weight	297.10 g/mol
Synonyms	2-Phenoxy-3-iodopyridine; 3-Iodo-2-phenoxypyridine; Pyridine, 3-iodo-2-phenoxy-; 3-Iodo-2-(phenoxy)pyridine
EINECS	Contact for details

Quality Control

Our 3-Iodo-2-Phenoxypyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.