Description

1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-1-[(1,1-Dimethylethyl)Dimethylsilyl]- is a high-purity, protected heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of complex pharmaceutical molecules and agrochemicals, offering precise reactivity for selective functionalization. It is primarily sought after by research and development teams in the pharmaceutical, biotechnology, and agrochemical sectors for constructing novel active ingredients and exploring new chemical entities.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of kinase inhibitors, receptor antagonists, and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its halogenated pyrrolopyridine core for bioactivity.
• Material Science: Serves as a precursor for creating functionalized organic materials and ligands for catalytic systems.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Academic & Contract Research: A valuable reagent for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Item	Detail
Product Name	1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-1-[(1,1-Dimethylethyl)Dimethylsilyl]-
CAS No.	754214-54-5
Molecular Formula	C13H19BrN2Si
Molecular Weight	311.30 g/mol
Synonyms	5-Bromo-1-(tert-butyldimethylsilyl)-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-[(1,1-dimethylethyl)dimethylsilyl]-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-TBDMS-7-azaindole; 5-Bromo-1-(TBDMS)-1H-pyrrolo[2,3-b]pyridine; 5-Bromo-1-(tert-butyldimethylsilyl)-7-azaindole; 5-Bromo-7-azaindole-1-TBDMS; 5-Bromo-1H-pyrrolo[2,3-b]pyridine, 1-(tert-butyldimethylsilyl) derivative
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 5-Bromo-1-[(1,1-Dimethylethyl)Dimethylsilyl]- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.