Description

1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 1-[(1,1-Dimethylethyl)Dimethylsilyl]- is a high-purity, protected heterocyclic aldehyde building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers requiring precise molecular architecture in complex chemical pathways. It is primarily utilized in pharmaceutical R&D and fine chemical production for the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates, particularly kinase inhibitors and other targeted therapeutics.
• Agrochemical Research: Used in the development of novel pesticides and herbicides, leveraging its unique fused heterocyclic structure.
• Material Science: Serves as a precursor for functionalized organic materials and ligands for catalytic systems.
• Academic & Contract Research: Employed in medicinal chemistry programs and method development for constructing challenging molecular scaffolds.
• Peptidomimetics & Bio-conjugation: The aldehyde functionality allows for selective conjugation and the creation of peptidomimetic structures.
• Chemical Biology Probes: Useful for creating labeled compounds and probes to study biological pathways and interactions.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 1-[(1,1-Dimethylethyl)Dimethylsilyl]-
CAS No.	754214-46-5
Molecular Formula	C14H22N2OSi
Molecular Weight	262.42 g/mol
Synonyms	1-[(tert-Butyl)dimethylsilyl]-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde; 1-(tert-Butyldimethylsilyl)-1H-pyrrolo[2,3-b]pyridine-5-carbaldehyde; 1H-Pyrrolo[2,3-b]pyridine-5-carboxaldehyde, 1-[(1,1-dimethylethyl)dimethylsilyl]-; 1-TBDMS-1H-pyrrolo[2,3-b]pyridine-5-carboxaldehyde; 5-Formyl-1-(tert-butyldimethylsilyl)-1H-pyrrolo[2,3-b]pyridine; 1-(tert-Butyldimethylsilyl)-5-formyl-1H-pyrrolo[2,3-b]pyridine; 1-TBDMS-7-azaindole-5-carboxaldehyde; 7-Azaindole-5-carboxaldehyde, 1-TBDMS protected
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-5-Carboxaldehyde, 1-[(1,1-Dimethylethyl)Dimethylsilyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with full analytical data are provided to support your R&D and scale-up activities.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.