Description

5-Ethynyl-N,n-Dimethyl-2-Pyridinamine is a specialized pyridine derivative featuring an ethynyl substituent, serving as a high-value building block in advanced organic synthesis. Its molecular architecture makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research institutions and pharmaceutical developers for applications in medicinal chemistry and materials science. The CAS number for this substance is 754190-29-9.

Application

5-Ethynyl-N,n-Dimethyl-2-Pyridinamine is utilized as a versatile synthon in various sophisticated chemical processes. Its applications include:

• Pharmaceutical Intermediate: Key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in developing new crop protection agents and herbicides due to its functional group versatility.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and coordination chemistry.
• Material Science: Incorporated into the development of organic semiconductors, conductive polymers, and advanced functional materials.
• Chemical Biology: Employed in probe development and bioconjugation strategies for studying biological systems.
• Academic & Industrial R&D: Fundamental research compound for exploring new organic reactions and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	5-Ethynyl-N,n-Dimethyl-2-Pyridinamine
CAS No.	754190-29-9
Molecular Formula	C9H10N2
Molecular Weight	146.19 g/mol
Synonyms	5-Ethynyl-N,N-dimethylpyridin-2-amine; 2-Pyridinamine, 5-ethynyl-N,N-dimethyl-; N,N-Dimethyl-5-ethynylpyridin-2-amine; 5-Ethynyl-2-(dimethylamino)pyridine
EINECS	Contact for details

Quality Control

Our production of 5-Ethynyl-N,n-Dimethyl-2-Pyridinamine adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized using advanced analytical techniques including NMR, HPLC, and GC-MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment. We support cGMP-compliant manufacturing for advanced research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being easily oxidized and hygroscopic, this material should be stored under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.