Description

2-Fluoro-4-Methyl-5-Nitro-Benzoic Acid Methyl Ester is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring strategically positioned fluorine, methyl, and nitro substituents, makes it a versatile intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for introducing fluorinated aromatic motifs which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can improve biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro and ester groups.
• Chemical Biology Probes: Employed in the synthesis of fluorinated probes and tags for imaging and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences market.

Basic Information

Product Name	2-Fluoro-4-Methyl-5-Nitro-Benzoic Acid Methyl Ester
CAS No.	753924-48-0
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Methyl 2-Fluoro-4-methyl-5-nitrobenzoate; Benzoic acid, 2-fluoro-4-methyl-5-nitro-, methyl ester; 2-Fluoro-4-methyl-5-nitrobenzoic acid methyl ester; Methyl 2-fluoro-4-methyl-5-nitrobenzoate; 753924-48-0; 2-Fluoro-4-methyl-5-nitro methyl benzoate
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-4-Methyl-5-Nitro-Benzoic Acid Methyl Ester is produced and tested under strict quality management protocols to ensure consistency and reliability for your critical synthesis workflows. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.