Description

Ethanone, 2-Chloro-1-[5-Chloro-2-[(1-Methyl-4-Piperidinyl)Amino]Phenyl]- is a high-purity, advanced pharmaceutical intermediate of significant commercial importance. Its value lies in its role as a critical building block for the synthesis of complex active pharmaceutical ingredients (APIs), enabling the development of targeted therapeutic agents. This compound is essential for research and production within the pharmaceutical and fine chemical industries, particularly for organizations focused on innovative drug discovery and development.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the manufacture of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and receptor-targeted therapies.
• Organic Synthesis Building Block: Utilized in multi-step organic synthesis for constructing complex molecular architectures containing chlorophenyl and piperidinylamino motifs.
• Research & Development (R&D): Serves as a crucial reagent in medicinal chemistry for lead optimization and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Employed in the scaled-up synthesis of specialty chemicals requiring high regioselectivity and purity.
• Contract Manufacturing (CMO/CDMO): Supplied to contract research and manufacturing organizations for custom synthesis projects and clinical trial material production.

Basic Information

Product Name	Ethanone, 2-Chloro-1-[5-Chloro-2-[(1-Methyl-4-Piperidinyl)Amino]Phenyl]-
CAS No.	753413-06-8
Molecular Formula	C14H16Cl2N2O
Molecular Weight	299.20 g/mol
Synonyms	2-Chloro-1-[5-chloro-2-[(1-methyl-4-piperidinyl)amino]phenyl]ethanone; 2-Chloro-1-(5-chloro-2-((1-methylpiperidin-4-yl)amino)phenyl)ethan-1-one; 753413-06-8; 2-Chloro-1-(5-chloro-2-((1-methyl-4-piperidinyl)amino)phenyl)ethanone; 1-(5-Chloro-2-((1-methylpiperidin-4-yl)amino)phenyl)-2-chloroethanone; 2-Chloro-1-(5-chloro-2-((1-methylpiperidin-4-yl)amino)phenyl)ethanone; 2-Chloro-1-[5-chloro-2-[(1-methyl-4-piperidyl)amino]phenyl]ethanone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Each batch is controlled via validated analytical methods, including HPLC, GC, and NMR, to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.