Description

2-Chloro-5-(Thiophen-2-Yl)Pyridine is a high-purity heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and agrochemicals, where its unique molecular scaffold enables precise structural modifications. Pharmaceutical researchers, agrochemical formulators, and specialty chemical manufacturers need it to create novel compounds with targeted biological activity. Its specific structure makes it valuable for constructing complex molecules in medicinal chemistry and crop protection research.

Application

• As a critical pharmaceutical intermediate in the synthesis of novel drug candidates, particularly in kinase inhibitor research.
• Building block for agrochemical active ingredients, including herbicides and fungicides.
• Precursor in the development of organic electronic materials and ligands for catalytic systems.
• Key starting material for custom synthesis and contract research organization (CRO) projects.
• Intermediate in the manufacture of dyes and pigments with specific optical properties.
• Research chemical for academic and industrial R&D in heterocyclic chemistry.

Basic Information

Item	Details
Product Name	2-Chloro-5-(Thiophen-2-Yl)Pyridine
CAS No.	753029-37-7
Molecular Formula	C9H6ClNS
Molecular Weight	195.67 g/mol
Synonyms	2-Chloro-5-(2-thienyl)pyridine; 5-(Thiophen-2-yl)-2-chloropyridine; 2-Chloro-5-(thiophen-2-yl)pyridine; 2-Chloro-5-(2-thiophenyl)pyridine; 753029-37-7; Pyridine, 2-chloro-5-(2-thienyl)-; 2-(2-Chloropyridin-5-yl)thiophene
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Thiophen-2-Yl)Pyridine is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our production adheres to cGMP principles where applicable, ensuring reliability for sensitive applications in pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.