Description

Azeto[1,2-a]isoxazolo[3,4-d]azepine (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for its role as a key building block in the research and development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in cutting-edge drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of new chemical entities.
• Library Synthesis: Employed in the generation of diverse compound libraries for high-throughput screening (HTS) in drug discovery campaigns.
• Process Chemistry Development: Acts as a key intermediate for scaling up synthetic routes from milligram to kilogram scale during API process development and optimization.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and synthetic organic chemistry.

Basic Information

Product Name	Azeto[1,2-a]isoxazolo[3,4-d]azepine (9Ci)
CAS No.	753021-64-6
Molecular Formula	C9H8N2O
Molecular Weight	160.18 g/mol
Synonyms	Azeto[1,2-a]isoxazolo[3,4-d]azepine; 1H-Azeto[1,2-a]isoxazolo[3,4-d]azepine; 753021-64-6; Azeto-isoxazolo-azepine; Fused tricyclic isoxazole-azepine derivative
EINECS	Contact for details

Quality Control

Our Azeto[1,2-a]isoxazolo[3,4-d]azepine (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to meet specific client or regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.