Description

7-Chloropyrrolo[1,2-C]Pyrimidine-3-Carboxylic Acid is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound is essential for medicinal chemistry research and the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapies. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex drug candidates, especially in oncology and anti-inflammatory research.
• Kinase Inhibitor Development: Serves as a core scaffold for designing and optimizing potent and selective kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel therapeutic targets.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex pyrrolopyrimidine-based molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis and process development projects.
• Academic Research: Used in university and institutional labs for exploratory chemistry and biochemical probe development.

Basic Information

Product Name	7-Chloropyrrolo[1,2-C]Pyrimidine-3-Carboxylic Acid
CAS No.	752981-45-6
Molecular Formula	C9H5ClN2O2
Molecular Weight	208.60 g/mol
Synonyms	7-Chloro-3-pyrrolo[1,2-c]pyrimidinecarboxylic acid; 7-Chloro-1H-pyrrolo[1,2-c]pyrimidine-3-carboxylic acid; 7-Chloro-1H-pyrrolo[1,2-c]pyrimidine-3-carboxylic acid; 7-Chloropyrrolo[1,2-c]pyrimidine-3-carboxylic acid; 752981-45-6; Pyrrolo[1,2-c]pyrimidine-3-carboxylic acid, 7-chloro-
EINECS	Contact for details

Quality Control

Our 7-Chloropyrrolo[1,2-C]Pyrimidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) with detailed chromatographic data are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contaminants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.