Description

1H-Cyclopenta[B]Pyridine-2-Carboxylicacid,Octahydro-,(2S,4As,7As)-(9Ci) is a high-purity, stereochemically defined advanced pharmaceutical intermediate (API) with the CAS number 752972-34-2. This compound is critical for the synthesis of complex, biologically active molecules, offering researchers and manufacturers a reliable building block with consistent stereochemical integrity. It is primarily utilized by pharmaceutical R&D teams and fine chemical producers engaged in the development of novel therapeutic agents, particularly in areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of active pharmaceutical ingredients (APIs) for central nervous system (CNS) and other therapeutic areas.
• Organic Synthesis Research: Used in academic and industrial laboratories for the construction of complex polycyclic and fused-ring molecular architectures.
• Medicinal Chemistry: Provides a scaffold for structure-activity relationship (SAR) studies and the development of new drug candidates.
• Asymmetric Catalysis Studies: Acts as a substrate or ligand precursor in the development and testing of new chiral catalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals requiring high stereochemical purity.

Basic Information

Product Name	1H-Cyclopenta[B]Pyridine-2-Carboxylicacid,Octahydro-,(2S,4As,7As)-(9Ci)
CAS No.	752972-34-2
Molecular Formula	C9H13NO2
Molecular Weight	167.21 g/mol
Synonyms	(2S,4aR,7aR)-Octahydro-1H-cyclopenta[b]pyridine-2-carboxylic acid; (2S,4aR,7aR)-Octahydro-2H-cyclopenta[b]pyridine-2-carboxylic acid; (2S,4aR,7aR)-1,2,3,4,4a,5,7,7a-Octahydrocyclopenta[b]pyridine-2-carboxylic acid; 752972-34-2; Cyclopentapyridine-2-carboxylic acid derivative; Chiral fused bicyclic amino acid.
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced under strict quality management systems. We provide comprehensive Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles, typically determined by HPLC, NMR, and chiral analysis. Our quality commitment aligns with cGMP principles for pharmaceutical starting materials, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.