Description

3-Pyrrolidinecarboxylic Acid, 4-Hydroxy-, Ethyl Ester, cis- (9Ci) is a high-purity chiral building block and intermediate of significant interest in advanced organic synthesis. Its value lies in its functionalized pyrrolidine core, which is a privileged scaffold found in numerous bioactive molecules and pharmaceuticals. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require a reliable source of high-quality, stereochemically defined intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of active pharmaceutical ingredients (APIs), particularly those targeting the central nervous system and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides that require specific stereochemistry for optimal activity.
• Ligand and Catalyst Development: Serves as a precursor for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The proline-like structure makes it valuable for constructing peptidomimetics and modifying peptide backbones to enhance stability and bioavailability.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value specialty chemicals for various industrial and research applications.

Basic Information

Product Name	3-Pyrrolidinecarboxylic Acid, 4-Hydroxy-, Ethyl Ester, cis- (9Ci)
CAS No.	752936-83-7
Molecular Formula	C7H13NO3
Molecular Weight	159.18 g/mol
Synonyms	cis-4-Hydroxypyrrolidine-3-carboxylic Acid Ethyl Ester; Ethyl cis-4-Hydroxypyrrolidine-3-carboxylate; (3R,4S)-4-Hydroxypyrrolidine-3-carboxylic Acid Ethyl Ester; (3S,4R)-4-Hydroxypyrrolidine-3-carboxylic Acid Ethyl Ester; 4-Hydroxy-3-pyrrolidinecarboxylic Acid Ethyl Ester, cis-; Ethyl 4-hydroxy-3-pyrrolidinecarboxylate; cis-4-Hydroxy-3-pyrrolidinecarboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our 3-Pyrrolidinecarboxylic Acid, 4-Hydroxy-, Ethyl Ester, cis- (9Ci) is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.