Description

4-Pentenoicacid,2-Amino-,2-Cyanoethylester,(2S)-(9Ci) is a chiral, non-proteinogenic amino acid derivative that serves as a sophisticated building block in advanced organic synthesis. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and bioactive compounds. It is primarily needed by research institutions and pharmaceutical companies engaged in peptide mimetics, enzyme inhibitor design, and the synthesis of constrained amino acid analogs for drug discovery programs.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptidomimetics Development: Used to incorporate constrained, unsaturated amino acid residues into peptide backbones to enhance metabolic stability and receptor selectivity.
• Enzyme Inhibitor Synthesis: Serves as a core structure for designing potent and selective inhibitors of proteases and other enzymes.
• Chemical Biology Probes: Employed in the creation of labeled or tagged molecular probes for studying biological pathways and protein function.
• Asymmetric Synthesis: Utilized as a chiral auxiliary or building block in stereoselective synthesis to introduce specific three-dimensional configurations into target molecules.
• Academic & Contract Research: A valuable reagent for methodological development in organic chemistry and for custom synthesis projects in CROs (Contract Research Organizations).

Basic Information

Product Name	4-Pentenoicacid,2-Amino-,2-Cyanoethylester,(2S)-(9Ci)
CAS No.	752192-23-7
Molecular Formula	C8H12N2O2
Molecular Weight	168.19 g/mol
Synonyms	(2S)-2-Amino-4-pentenoic acid 2-cyanoethyl ester; 2-Cyanoethyl (2S)-2-amino-4-pentenoate; L-2-Amino-4-pentenoic acid 2-cyanoethyl ester; (S)-2-Amino-4-pentenoic acid 3-cyanopropyl ester; 4-Pentenoic acid, 2-amino-, 2-cyanoethyl ester, (2S)-; 2-Amino-4-pentenoic acid cyanoethyl ester (S-enantiomer); UNII-7K4I8P3Q4F (component); 2-Propenylglycine 2-cyanoethyl ester (S-form)
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral chromatography, and NMR spectroscopy. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid or clear to pale yellow liquid/oil
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.