Description

Carbamic Acid, (2-Hydroxy-1-Methylpropyl)-, 1,1-Dimethylethyl Ester (9Ci) is a specialized carbamate derivative that serves as a valuable protected intermediate in advanced organic synthesis. This compound is critical for researchers and manufacturers requiring high-purity building blocks for the development of complex molecules, particularly in the pharmaceutical sector. Its structure makes it a key precursor for synthesizing active pharmaceutical ingredients (APIs) and other fine chemicals where precise molecular control is paramount.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and metabolic disorder treatments.
• Peptide Mimetics & Prodrug Synthesis: Used to introduce carbamate-protected amine and alcohol functionalities, enabling the creation of peptide analogs and prodrugs with enhanced stability and bioavailability.
• Agrochemical Research: Serves as a precursor in the development of new-generation herbicides and insecticides, where the carbamate moiety is a common pharmacophore.
• Polymer Chemistry: Employed in the synthesis of functional monomers for specialty polymers, including polyurethanes and polycarbonates with tailored properties.
• Chemical Biology & Proteomics: Utilized as a reagent for modifying proteins and enzymes or creating activity-based probes to study biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	Carbamic Acid, (2-Hydroxy-1-Methylpropyl)-, 1,1-Dimethylethyl Ester (9Ci)
CAS No.	752135-63-0
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	tert-Butyl (2-hydroxy-1-methylpropyl)carbamate; N-(tert-Butoxycarbonyl)-2-hydroxy-1-methylpropylamine; 1,1-Dimethylethyl N-(2-hydroxy-1-methylpropyl)carbamate; BOC-2-Hydroxy-1-methylpropylamine; (2-Hydroxy-1-methylpropyl)carbamic acid tert-butyl ester; tert-Butyl (1-methyl-2-hydroxypropyl)carbamate; N-BOC-2-Hydroxy-1-methylpropylamine
EINECS	Contact for details

Quality Control

Our Carbamic Acid, (2-Hydroxy-1-Methylpropyl)-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates, ensuring reliability for your most critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Area %)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.