Description

1'-(6-Chloro-4-(Trifluoromethyl)Pyridin-2-Yl)-Piperazine is a high-value, multi-functional heterocyclic building block and intermediate of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a halogenated, trifluoromethylated pyridine ring with a piperazine moiety, enabling precise modifications to enhance the physicochemical properties of target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly in areas like kinase inhibitors, CNS agents, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for designing functional molecules used in organic electronics, liquid crystals, or advanced polymers.
• Chemical Biology Probe Development: Employed to build molecular tools for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring complex, fluorinated heterocyclic structures.

Basic Information

Product Name	1'-(6-Chloro-4-(Trifluoromethyl)Pyridin-2-Yl)-Piperazine
CAS No.	750628-50-3
Molecular Formula	C10H9ClF3N3
Molecular Weight	263.65 g/mol
Synonyms	2-(Piperazin-1-yl)-6-chloro-4-(trifluoromethyl)pyridine; 6-Chloro-4-(trifluoromethyl)-2-(1-piperazinyl)pyridine; 1-(6-Chloro-4-(trifluoromethyl)pyridin-2-yl)piperazine; 750628-50-3; 2-Piperazin-1-yl-6-chloro-4-trifluoromethylpyridine; 6-Chloro-2-piperazin-1-yl-4-(trifluoromethyl)pyridine
EINECS	Contact for details

Quality Control

Our 1'-(6-Chloro-4-(Trifluoromethyl)Pyridin-2-Yl)-Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality ensures reliable performance in your most demanding synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong acids and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.