Description

Methyl 6-Bromo-2-Chloro-3-Methoxybenzoate is a high-purity, multi-substituted benzoate ester derivative serving as a critical building block in advanced organic synthesis. Its value lies in providing a versatile, functionalized aromatic core for constructing complex molecules, particularly in pharmaceutical research and development. This intermediate is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality raw materials for their synthetic pipelines.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing substituents.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) working on client-specific molecules.
• Academic and R&D Laboratories: Used in university and institutional research for methodological studies and exploring new chemical reactions.

Basic Information

Product Name	Methyl 6-Bromo-2-Chloro-3-Methoxybenzoate
CAS No.	750586-08-4
Molecular Formula	C9H8BrClO3
Molecular Weight	279.51 g/mol
Synonyms	6-Bromo-2-chloro-3-methoxybenzoic acid methyl ester; Methyl 6-bromo-2-chloro-3-methoxybenzoate; Benzoic acid, 6-bromo-2-chloro-3-methoxy-, methyl ester; 2-Chloro-6-bromo-3-methoxybenzoic acid methyl ester; Methyl 2-chloro-6-bromo-3-methoxybenzoate; 3-Methoxy-6-bromo-2-chlorobenzoic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 6-Bromo-2-Chloro-3-Methoxybenzoate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical processes. Each lot is analyzed using advanced techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting all critical quality attributes are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Any individual impurity ≤0.5%; Total impurities ≤2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.