Description

Ethanone, 1-(2-Amino-4-Pyridinyl)-2-Bromo- (9Ci) is a specialized brominated pyridine derivative, serving as a high-value synthetic intermediate in advanced organic chemistry. Its core value lies in providing a reactive halogen handle and a protected amine group, enabling precise molecular construction for complex target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially those targeting kinase inhibition or requiring specific heterocyclic scaffolds.
• Agrochemical Research: Used in developing novel pesticides and herbicides, where the pyridine core is a common structural motif for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers and organic electronic materials.
• Chemical Biology Probe Synthesis: Employed to create labeled compounds or molecular probes for studying biological pathways and target engagement.
• Cross-Coupling Reactions: The bromo substituent makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Negishi, or Buchwald-Hartwig amination.
• Ligand and Catalyst Development: Used to synthesize novel chelating ligands or organocatalysts for asymmetric synthesis.

Basic Information

Product Name	Ethanone, 1-(2-Amino-4-Pyridinyl)-2-Bromo- (9Ci)
CAS No.	750571-38-1
Molecular Formula	C7H7BrN2O
Molecular Weight	215.05 g/mol
Synonyms	2-Bromo-1-(2-amino-4-pyridinyl)ethanone; 1-(2-Amino-4-pyridinyl)-2-bromoethanone; 2-Bromo-1-(2-amino-4-pyridin-1-ium-1-yl)ethan-1-one; 2-Bromo-1-(2-aminopyridin-4-yl)ethanone; Bromo(2-amino-4-pyridinyl)methanone; (2-Amino-4-pyridyl) bromomethyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(2-Amino-4-Pyridinyl)-2-Bromo- (9Ci) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container sealed under an inert atmosphere if long-term storage is required to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.