Description

1,4-Dioxaspiro[4.4]Nonane-7-Carboxylicacid,8-Amino-,(7R,8S)-Rel-(9Ci) CAS NO 750567-88-5 is a high-purity, stereochemically defined spirocyclic compound that serves as a critical chiral building block and advanced pharmaceutical intermediate. Its unique fused ring structure and functional groups make it invaluable for constructing complex molecular architectures with precise three-dimensional control. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of complex drug candidates, particularly for central nervous system (CNS) and antiviral therapeutics.
• Agrochemical Research: Used in the development of novel, stereospecific pesticides and herbicides where the specific (7R,8S) configuration is crucial for bioactivity.
• Asymmetric Catalysis: Employed as a ligand precursor or a chiral auxiliary in catalytic reactions to induce enantioselectivity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating spirocyclic and bridged compounds in specialty chemical manufacturing.
• Academic & R&D: Utilized in organic chemistry research for methodology development and the study of spirocyclic compound properties.

Basic Information

Product Name	1,4-Dioxaspiro[4.4]Nonane-7-Carboxylicacid,8-Amino-,(7R,8S)-Rel-(9Ci)
CAS No.	750567-88-5
Molecular Formula	C9H13NO4
Molecular Weight	199.20 g/mol
Synonyms	(7R,8S)-8-Amino-1,4-dioxaspiro[4.4]nonane-7-carboxylic acid; rel-(7R,8S)-8-Amino-1,4-dioxaspiro[4.4]nonane-7-carboxylic acid; 8-Amino-1,4-dioxaspiro[4.4]nonane-7-carboxylic acid, (7R,8S)-rel-; 1,4-Dioxaspiro[4.4]nonane-7-carboxylic acid, 8-amino-, (7R,8S)-rel-; Spirocyclic amino acid derivative; Chiral spiroketal amino acid
EINECS	Contact for details

Quality Control

Our production of 1,4-Dioxaspiro[4.4]Nonane-7-Carboxylicacid,8-Amino-,(7R,8S)-Rel-(9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. All material is characterized using advanced analytical techniques including chiral HPLC, NMR, and mass spectrometry to confirm identity, stereochemical purity, and potency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment, and we support compliance with cGMP and ISO 9001 standards for pharmaceutical-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic; therefore, containers should be kept tightly sealed to exclude moisture. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.