Description

2-Piperidinecarboxylicacid,4-Ethyl-,2,2-Dimethylpropylester,(2R,4R)-(9Ci) is a high-purity, stereochemically defined chiral piperidine derivative, serving as a critical advanced intermediate in modern organic synthesis. Its precise stereochemistry and functionalized structure make it an invaluable building block for constructing complex molecules with high enantiomeric purity. This compound is primarily utilized by research institutions and pharmaceutical development teams working on novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides where specific stereochemistry is required for biological activity.
• Catalyst and Ligand Development: Serves as a precursor for creating novel chiral catalysts and ligands used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of complex, high-value specialty chemicals for electronics and material science applications.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-Piperidinecarboxylicacid,4-Ethyl-,2,2-Dimethylpropylester,(2R,4R)-(9Ci)
CAS No.	750556-75-3
Molecular Formula	C13H25NO2
Molecular Weight	227.34 g/mol
Synonyms	(2R,4R)-4-Ethyl-2-piperidinecarboxylic acid 2,2-dimethylpropyl ester; 4-Ethyl-D-pipecolic acid neopentyl ester; (2R,4R)-4-Ethylpipecolic acid neopentyl ester; Neopentyl (2R,4R)-4-ethylpipecolate; (R,R)-4-Ethyl-2-piperidinecarboxylic acid 2,2-dimethylpropyl ester; 750556-75-3; (2R,4R)-rel-4-Ethyl-2-piperidinecarboxylic acid 2,2-dimethylpropyl ester
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality protocols to ensure batch-to-batch consistency and high enantiomeric excess (ee). Quality is verified through advanced analytical techniques including Chiral HPLC, GC, and NMR. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.