Description

n-(4-Chloro-3-Formylpyridin-2-Yl)Pivalamide is a high-purity, functionalized pyridine derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical pharmaceutical intermediate, prized for its reactive aldehyde and amide functionalities which enable the construction of complex molecular architectures. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its halogenated pyridine core.
• Chemical Research & Development: Serves as a versatile precursor for heterocyclic chemistry, enabling the introduction of the pivaloyl amide and formyl groups into target molecules.
• Ligand and Catalyst Preparation: The formyl and amide groups make it a suitable starting material for synthesizing specialized ligands for metal catalysis.
• Custom Synthesis Projects: Employed in contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis under cGMP or research-grade conditions.

Basic Information

Product Name	n-(4-Chloro-3-Formylpyridin-2-Yl)Pivalamide
CAS No.	749925-46-0
Molecular Formula	C11H11ClN2O2
Molecular Weight	238.67 g/mol
Synonyms	2-Pivalamido-4-chloro-3-pyridinecarboxaldehyde; 4-Chloro-3-formyl-2-pyridinyl-pivalamide; Pivalic acid (4-chloro-3-formyl-2-pyridinyl)amide; 749925-46-0; 4-Chloro-3-formylpyridin-2-yl-pivalamide; N-(4-Chloro-3-formyl-2-pyridinyl)-2,2-dimethylpropanamide
EINECS	Contact for details

Quality Control

Our n-(4-Chloro-3-Formylpyridin-2-Yl)Pivalamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for sensitive synthesis applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). This compound is easily oxidized; for long-term storage, consider under an inert atmosphere (nitrogen or argon) to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.