Description

3-Chloro-2-(Trifluoromethyl)-Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chlorine and trifluoromethyl substituents, provides exceptional reactivity and physicochemical properties for creating novel compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients with enhanced efficacy and stability.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the manufacture of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group often enhances biological activity and environmental stability.
• Material Science: Serves as a precursor for functional materials, including liquid crystals, organic light-emitting diodes (OLEDs), and advanced polymers.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new reaction pathways and creating complex molecular architectures.
• Ligand and Catalyst Design: Employed in the synthesis of specialized ligands for metal catalysis and asymmetric synthesis.

Basic Information

Product Name	3-Chloro-2-(Trifluoromethyl)-Pyridine
CAS No.	749875-32-9
Molecular Formula	C6H3ClF3N
Molecular Weight	181.54 g/mol
Synonyms	2-(Trifluoromethyl)-3-chloropyridine; 3-Chloro-2-trifluoromethylpyridine; 3-Chloro-α,α,α-trifluoro-2-picoline; Pyridine, 3-chloro-2-(trifluoromethyl)-; 749875-32-9
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-(Trifluoromethyl)-Pyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry standards for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.