Description

5-Bromo-2-Trifluoromethyl-Isonicotinic Acid CAS NO 749875-16-9 is a high-purity, multifunctional heterocyclic building block designed for advanced chemical synthesis. This compound is valued for its unique molecular architecture, combining a bromine substituent with a trifluoromethyl group on a pyridine carboxylic acid core, which is critical for modulating the physicochemical properties of target molecules. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for creating molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the design and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as those used in OLEDs or semiconductors, due to its electron-deficient aromatic system.
• Custom Synthesis and Contract Manufacturing: A vital starting material for custom chemical synthesis services catering to R&D and pilot-scale production.
• Chemical Biology Probes: Useful for synthesizing molecular probes and tags used in biochemical and diagnostic research.

Basic Information

Product Name	5-Bromo-2-Trifluoromethyl-Isonicotinic Acid
CAS No.	749875-16-9
Molecular Formula	C7H3BrF3NO2
Molecular Weight	269.99 g/mol
Synonyms	5-Bromo-2-(trifluoromethyl)pyridine-4-carboxylic acid; 4-Pyridinecarboxylic acid, 5-bromo-2-(trifluoromethyl)-; 5-Bromo-2-trifluoromethylisonicotinic acid; 5-Bromo-2-(trifluoromethyl)isonicotinic acid; 5-Bromo-2-(trifluoromethyl)-4-pyridinecarboxylic acid; 749875-16-9; 5-Bromo-2-trifluoromethyl-4-pyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Trifluoromethyl-Isonicotinic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.